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Bupropion (Generic Wellbutrin®)
Wellbutrin® is an antidepressant that works by affecting two chemicals in the brain that are believed to help regulate your mood (dopamine and norepinephrine).
Bupropion
Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Common Brand Name(s)
Bupropion
Generic Wellbutrin
Wellbutrin®
Uses
This medication is used to treat depression.
How
to Use
This medication may be taken with food if stomach upset occurs.
Take doses at regularly scheduled times each day. Do not take
more or less medication than prescribed and follow your doctor's
instructions carefully. Taking more than the recommended dose
of bupropion will increase your risk of having a seizure.
Do not stop taking this medication without notifying your
doctor. Since this drug may cause sleeplessness at first,
it is best not to take this near bedtime. It may take 4 weeks
or more before the full effects of this medication are noticed.
Side
Effects
This medication is generally well tolerated. Dry mouth, headache,
increased sweating, nausea/vomiting, constipation, anxiety,
fatigue and blurred vision may occur. If these effects persist
or worsen, notify your doctor. Report promptly: unusual weight
loss or gain, palpitations, agitation, trouble sleeping. Unlikely
but report promptly: tremor, dizziness, fainting, mood changes,
slowed movements, difficulty urinating, decreased sex drive,
drowsiness. Very unlikely but report promptly: seizures, mental
problems, fever, muscle aches, yellowing of the eyes or skin.
In the unlikely event you have an allergic reaction to this
drug, seek medical attention immediately. Symptoms may include
trouble breathing, rash, itching, swelling, or severe dizziness.
If you notice other effects not listed above, contact your
doctor or pharmacist.
Precautions
Before taking bupropion, tell your doctor if you have: history
of seizures or head injury or brain tumor, heart disease,
liver or kidney disease, eating disorder, diabetes, alcohol
dependence, any allergies, the intent to quit smoking. Because
of the possibility this drug will make you dizzy and affect
coordination, do not drive or operate machinery until you
get used to the drug's effects. Limit or avoid consumption
of alcoholic beverages; alcohol can increase your risk of
seizures. Chronic alcohol users who suddenly stop the intake
of alcohol while taking bupropion may increase the risk of
having seizures. Suddenly stopping certain tranquilizers (e.g.,
diazepam, chlordiazepoxide) is not recommended because doing
so may increase the risk of having seizures. Elderly patients
may be more sensitive to the effects of this drug. Tell your
doctor if you are pregnant or plan to become pregnant before
taking this drug. This drug passes into breast milk. Because
of the potential risk to the infant, breast-feeding while
using this drug is not recommended. Consult your doctor before
breast-feeding.
Drug
Interactions
Before taking bupropion tell your doctor of all nonprescription
and prescription medications you may use especially: MAO inhibitors
(e.g., isocarboxazid, phenelzine, tranylcypromine, pargyline,
selegiline, linezolid, furazolidone), levodopa, ritonavir,
corticosteroids (e.g. prednisone), sedatives, adrenaline-like
stimulants (e.g., ephedrine), products containing nicotine
(e.g., patches or gum). Also report use of drugs which might
increase seizure risk (decrease seizure threshold) such as:
phenothiazines (e.g., chlorpromazine), tricyclic antidepressants
(e.g., amitriptyline), isoniazid (INH), theophylline. Excess
caffeine intake can increase the chance of seizures with this
drug. Check all nonprescription/prescription drug labels for
caffeine. Consult your doctor or pharmacist. A certain product
used to help quit smoking contains bupropion. Do not take
that product while using this one. Do not start or stop any
medicine without doctor or pharmacist approval.
Overdose
If overdose is suspected, contact your local poison control
center or emergency room immediately. Symptoms of overdose
may include seizures, hallucinations, rapid heart rate, and
loss of consciousness.
Notes
Do not allow anyone else to take this medication.
Missed
Dose
Take any missed dose as soon as possible but not if it is
within 4 hours of the next dose. If it is time for the next
dose, skip the missed dose and resume your regular schedule.
Do not "double-up" the dose.
Storage
Store at room temperature and keep away from moisture and
sunlight. Do not store in the bathroom.
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